Abstracts from the CAL/ACEP Scientific Assembly, Long Beach, CA 2002
نویسندگان
چکیده
Objective: Pediatric cases comprise approximately 22% of rattlesnake envenomations in the U.S. The recent introduction of Crotaline Fab antivenom and withdrawal from the market of the traditional antivenom preparation has changed the way rattlesnake envenomation is treated. Although in some hospitals Crotaline Fab antivenom may be the only antivenom currently available, there is little data regarding its use in children. Our objective is to provide the first data regarding safety and effectiveness of this new drug in the pediatric population. Methods: Data was collected prospectively and retrospectively for all pediatric rattlesnake envenomations treated at two urban hospitals during the year 2001. Cases were included if there were signs of envenomation at presentation, patient age 13 years or less, and administration of Crotaline Fab antivenom. Cases were excluded if Antivenin Crotalidae Polyvalent was given. Primary outcome variables were snakebite severity scores throughout the course of therapy, number of vials of Crotaline Fab antivenom given, occurrence of allergic reactions, need for surgical therapy, and the presence of permanent sequelae or serum sickness identified at telephone followup. Results: In the 12 study cases, age ranged from 14 months to 13 years. (mean=6.9, sd=4.2) Presentation snakebite severity scores ranged from 2 to 9. (mean=5.3, sd=2.3) Total Crotaline Fab antivenom doses ranged from 4 to 22 vials. (mean=12.7, sd=5.4) Initial control of symptoms was achieved with 4-16 vials (mean=7.7, sd=3.7) and severity scores stabilized or improved within 24 hours in all patients. Recurrence of local swelling occurred in one case despite scheduled doses of antivenom. No cases required surgical intervention and no permanent sequelae were identified. No immediate or delayed hypersensitivity reactions occurred. Conclusion: In this group of pediatric patients treated for rattlesnake envenomation, Crotaline Fab antivenom was safe and appeared to be effective. References
منابع مشابه
CAL/ACEP Joins CAL/AAEM and UC Irvine in Sponsoring the Western Journal of Emergency Medicine
When you look at the Western Journal of Emergency Medicine's (WestJEM) cover and masthead this month you will see something new: two logos side by side, the California Chapter of AAEM (CAL/AAEM) and the California Chapter of ACEP (CAL/ACEP). Based on an agreement forged this year, CAL/ACEP has joined CAL/AAEM and the Department of Emergency Medicine at the University of California, Irvine (UCI)...
متن کاملOption Wealth and Bequest Values: The Value of Protecting Future Generations from the Health Risks of Nuclear Waste Storage For Presentation at the Annual Meetings of the AAEA in Long Beach CA
متن کامل
A Web-Based CAL System on Computer Architecture and Assembly Language Programming
This paper introduces a CAL system on Computer Architecture and Assembly Language Programming. The ability of the system is to simulate a computer system that allows the student to understand the whole process from software programming to hardware execution. Multimedia and web-based technologies are applied in the system. The proposed system helps the student to connect theory to practice more ...
متن کاملSelf-Organizing Into Winning Teams: Understanding the Mechanisms That Drive Successful Collaborations
Contemporary teams are self-assembling with increasing frequency, meaning the component members are choosing to join forces with some degree of agency rather than being assigned to work with one another. However, the majority of the teams literature up until this point has focused on randomly assigned or staffed teams. Thus, the purpose of the current study was to investigate how people do form...
متن کاملHolocene temperature changes in northern Fennoscandia reconstructed from chironomids using Bayesian modelling
The recently developed Bayesian multinomial calibration model, Bummer, was applied to the fossil chironomid assemblages of a lake situated at the present tree-line in northern Fennoscandia to reconstruct patterns in Holocene climates. The results are compared with inferences derived using non-Bayesian weighted averaging partial least-squares regression. The reconstruction exhibits both long-ter...
متن کامل